{"id":7395,"date":"2025-06-28T18:04:49","date_gmt":"2025-06-28T18:04:49","guid":{"rendered":"https:\/\/ijssass.com\/journal\/glycaemic-response-to-three-main-meals-or-five-smaller-meals-for-patients-on-rapid-acting-insulin\/"},"modified":"2025-06-29T05:07:52","modified_gmt":"2025-06-29T05:07:52","slug":"glycaemic-response-to-three-main-meals-or-five-smaller-meals-for-patients-on-rapid-acting-insulin","status":"publish","type":"post","link":"https:\/\/ijssass.com\/journal\/glycaemic-response-to-three-main-meals-or-five-smaller-meals-for-patients-on-rapid-acting-insulin\/","title":{"rendered":"Glycaemic response to three main meals or five smaller meals for patients on rapid-acting insulin"},"content":{"rendered":"

This article was originally published as: Glycaemic response to three main meals or five smaller meals for patients on rapid-acting insulin<\/strong><\/p>\n

Original Article Link: Read Original Article<\/a><\/p>\n

Download PDF: Click Here to Download PDF<\/a><\/p>\n

Abstract<\/h2>\n

Objective: To compare seven-point blood glucose profiles of patients with type 2 diabetes mellitus using rapid-acting insulin, when daily calories were provided as three main meals versus five smaller meals (three main meals + two snacks), while maintaining the same total daily calorie intake and composition of carbohydrates, fats and protein.
\nDesign: A cross-over study.
\nSetting: Xiamen University Zhongshan Hospital, China.
\nSubjects: Over a four week period, 22 patients with type 2 diabetes mellitus using fixed doses of rapid-acting insulin were recruited into the study. Two patients failed to complete the study and data from the remaining 20 subjects were analysed.
\nIntervention: The subjects using fixed doses of rapid-acting insulin were randomised to five smaller meals versus three main meals treatment periods. Glycaemic response to each meal pattern was measured by seven-point blood glucose profiles.
\nMain Outcome Measures: The mean seven-point blood glucose levels and the risk of hypoglycaemia.
\nResults: The mean seven-point blood glucose levels with the pattern of eating five smaller meals was lower than that with three main meals (9.1mmol\/L vs. 9.5mmol\/L), however the difference was not statistically significant (F=0.524, P=0.474). There were no differences in mean blood glucose levels across the seven-point profile. The risk of hypoglycaemia was also not statistically significant.
\nConclusions: This suggests that it may be unnecessary for patients using rapid-acting insulin to have five smaller meals.<\/p>\n

Authors<\/h2>\n
    \n
  • Zhaolin Meng<\/li>\n
  • Jane Overland<\/li>\n
  • Xingping Shen<\/li>\n
  • Xiaobin Wu<\/li>\n
  • Yuanyuan Wang<\/li>\n
  • Yunyun Liu<\/li>\n<\/ul>\n

    Keywords<\/h2>\n

    type 2 diabetes mellitus, insulin aspart, glycaemic control, diet<\/p>\n

    References<\/h2>\n

    References not available for this article.<\/p>\n","protected":false},"excerpt":{"rendered":"

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