{"id":4375,"date":"2025-06-18T18:19:29","date_gmt":"2025-06-18T18:19:29","guid":{"rendered":"https:\/\/ijssass.com\/journal\/validite-de-test-de-diagnostic-rapide-des-arboviroses-lors-des-fievres-indifferenciees-dans-la-ville-de-kinshasa-cas-du-virus-de-la-dengue\/"},"modified":"2025-06-18T19:59:55","modified_gmt":"2025-06-18T19:59:55","slug":"validite-de-test-de-diagnostic-rapide-des-arboviroses-lors-des-fievres-indifferenciees-dans-la-ville-de-kinshasa-cas-du-virus-de-la-dengue","status":"publish","type":"post","link":"https:\/\/ijssass.com\/journal\/validite-de-test-de-diagnostic-rapide-des-arboviroses-lors-des-fievres-indifferenciees-dans-la-ville-de-kinshasa-cas-du-virus-de-la-dengue\/","title":{"rendered":"VALIDITE DE TEST DE DIAGNOSTIC RAPIDE DES ARBOVIROSES LORS DES FIEVRES INDIFFERENCIEES DANS LA VILLE DE KINSHASA CAS DU VIRUS DE LA DENGUE"},"content":{"rendered":"

This article was originally published as: VALIDITE DE TEST DE DIAGNOSTIC RAPIDE DES ARBOVIROSES LORS DES FIEVRES INDIFFERENCIEES DANS LA VILLE DE KINSHASA CAS DU VIRUS DE LA DENGUE<\/strong><\/p>\n

Original Article Link: Read Original Article<\/a><\/p>\n

Download PDF: Click Here to Download PDF<\/a><\/p>\n

Abstract<\/h2>\n

Avec la r\u00e9duction de la charge du paludisme parmi les causes de la fi\u00e8vre, il est indispensable d’identifier les autres \u00e9tiologies afin d’am\u00e9liorer la prise en charge des patients. Pour ce diagnostic, il faut un plateau technique simple pour des pays \u00e0 faible revenu. Parmi les causes des fi\u00e8vres d’origine ind\u00e9termin\u00e9es figurent les causes virales notamment la dengue. Un test de diagnostic rapide, le NS1, a \u00e9t\u00e9 mis au point. Une \u00e9tude de validation du NS1 a \u00e9t\u00e9 men\u00e9e parmi les patients f\u00e9briles qui ont consult\u00e9 le centre hospitalier Lisungi de la zone de sant\u00e9 de Mont Ngafula 1 \u00e0 Kinshasa en R\u00e9publique d\u00e9mocratique du Congo. Le test de r\u00e9f\u00e9rence a \u00e9t\u00e9 la PCR\/Dengue r\u00e9alis\u00e9e \u00e0 l’Institut de m\u00e9decine tropicale d’Anvers tandis que le NS1 a \u00e9t\u00e9 r\u00e9alis\u00e9 sur place \u00e0 Lisungi.<\/p>\n

Au total 342 patients ont \u00e9t\u00e9 inclus. La pr\u00e9valence de la dengue a \u00e9t\u00e9 estim\u00e9e \u00e0 6.1% en consid\u00e9rant les r\u00e9sultats de la PCR. La sensibilit\u00e9 et la sp\u00e9cificit\u00e9 de NS1 ont \u00e9t\u00e9 estim\u00e9es respectivement \u00e0 90.0% et \u00e0 100.0% en consid\u00e9rant la PCR comme le Gold standard. La Valeur Pr\u00e9dictive Positive et la Valeur Pr\u00e9dictive N\u00e9gative ont \u00e9t\u00e9 estim\u00e9es respectivement \u00e0 100.0% et 99.4%.<\/p>\n

Le virus de la dengue est en circulation \u00e0 Kinshasa en RDC. Le test de diagnostic rapide NS1 devra \u00eatre introduit dans les structures sanitaires de la RDC afin d’accro\u00eetre le plateau technique pour \u00e9lucider les causes de fi\u00e8vre et mettre le clinicien en confiance. Cette confiance permettra d’\u00e9viter une prescription inutile des antipaludiques et des antibiotiques.<\/p>\n

Authors<\/h2>\n
    \n
  • Freddy KATSHONGO MUSHINDUA (Chef travaux, ISTM KINSHASA)<\/li>\n
  • Mike KAKULE MUSHINDUA (Assistant, ISTM KINSHASA)<\/li>\n
  • Jean Pierre VAN GEERTRUYDEN (Professeur, UNIVERSITY OF ANTWERP, BELGIUM)<\/li>\n
  • SAM PROESMANS (Professeur, ITM ANTWERP, BELGIUM)<\/li>\n
  • VEERLE VANLERBERGHE (Professeur, ITM ANTWERP, BELGIUM)<\/li>\n
  • Jean LUFULUABO KASUYI (Professeur, ISTM KINSHASA)<\/li>\n
  • Pascal LUTUMBA TSHINDELE (Professeur, UNIVERSITE DE KINSHASA)<\/li>\n<\/ul>\n

    Keywords<\/h2>\n

    Etiologie, Fi\u00e8vre indiff\u00e9renci\u00e9e, Arbovirose, Estimation, Test NS1, Denge<\/p>\n

    References<\/h2>\n
      \n
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    15. B. WEBOGRAPHIE<\/li>\n
    16. http:\/\/fr.wikipedia.org\/wiki\/Arboviroses, le 22 Mai 2018. 143.<\/li>\n
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    19. http:\/\/fr.wikipedia.org\/wiki\/virus de la dengue; Le 15 juin 2018<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

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